CICA – CELIAC, IBS AND CROHN’S ARRAY

WHAT IS THE CICA TEST?

The CICA test measures gut health on the genetic, antibody and cellular levels. The CICA test includes the following tests:

  • Genetic – HLA Typing for Celiac Disease (HLA-DQ2.5 and HLA-DQ8; ATG16L1 + N0D2)
  • Antibody/Serological
    • Total Serum IgA
    • Tissue Transgluatminase Antibody (tTG) – IgA and IgG
    • Deamidated Gliadin Peptide (DGP) Antibody – IgA and IgG
    • Anti-Saccharomyces Cerevisiae Antibody (ASCA)

AM I REQUIRED TO FAST FOR THIS LAB TEST?

No.

WHAT IS THE PRICE FOR A CICA TEST?

$879.00

*Price may vary by location – contact your local ANY LAB TEST NOW®

HOW LONG WILL IT TAKE TO GET MY LAB TEST RESULTS?

It takes about 5 business days for your store to receive the printable color results from the lab to provide to you, which you can pick up from your ANY LAB TEST NOW location at your convenience.

DESCRIPTION:

One in every 133 Americans suffers from celiac disease totaling 3 million Americans. 85% of these people have not been diagnosed so they either struggle along trying to figure out what foods to avoid on their own and suffer from painful and sometimes, debilitating symptoms of celiac disease. Several millions more suffer from gluten intolerance, which can be very painful and can get worse over time. Intolerances differ significantly from allergies. Unlike allergies, intolerances may vary from situation to situation, while an allergy always produces the same reaction. Intolerances are caused by the body’s inability to process specific substances and may cause bloating, digestive problems such as gas and/or diarrhea, fatigue, headaches and even the inability to lose weight or weight gain.

True celiac disease, unlike gluten intolerance, is genetically based and carried from parents or grandparents to their children. If gluten is ingested the villi in the small intestine are damaged over time reducing the villi’s ability to absorb needed nutrients from food and increasing abdominal discomfort. Functional gastrointestinal disorders affect 2 in every 5 Americans and include Irritable Bowel Syndrome (IBS), Celiac Disease, Functional Dyspepsia (indigestion), Ulcerative Colitis and Crohn’s Disease. The CICA test can help to determine if you have Celiac Disease or some other gastrointestinal disorder so that you can properly treat your symptoms.

WHY DO I NEED IT?

Are you experiencing abdominal pain, changes in bowel habits weight gain or weight loss, chronic digestive discomfort, nausea and diarrhea, obesity or the inability to lose weight? Do you have a family history of celiac disease?

Trying to identify the cause of chronic discomfort can be complicated when it doesn’t seem linked to a specific food, but the CICA test can help. The genetic testing portion of the profile will determine the likelihood that what you are suffering is celiac disease, as opposed to gluten intolerance. 95% of people who have either the gene HLA-DQ2.5 or HLA-DQ8 have celiac disease. Antibody tests in the profile will indicate whether specific antibodies are missing and others have developed causing damage to the small intestines and can indicate the presence of celiac disease as well as differentiate between ulcerative colitis and Crohn’s disease, both of which have similar symptoms to celiac disease.

OTHER RELEVANT TESTS:

People who purchased the CICA test also considered the Basic Check Up or a Comprehensive Sensitivity or Intolerance Panel.

TEST DETAILS:

The test results are provided in a report that graphically represents the test result information.

Genetic Testing

The test results will determine whether you have the genes responsible for susceptibility to celiac disease, IBS and Crohn’s disease.

Antibody Testing

Total Serum IgA: Celiac disease patients are more likely to be low in this common antibody. A low result could indicate celiac disease.

Tissue Transglutaminase Antibody (tTG): tTG is produced in the small intestine where gluten causes initial inflammation. The irritated immune cells respond by producing tTG. A very high result indicates that celiac disease is present. If the result is only slightly high, it may indicate celiac disease but should be considered with other test results.

Deamidated Gliadin Peptide (DGP): The presence of DGP indicates gluten gut damage. The irritated immune cells respond by producing DGP. A very high level indicates likely celiac disease.

Anti-Saccharomyces Cerevisiae Antibody (ASCA): Because there is overlap in the symptoms of IBS, this antibody test will differentiate between Crohn’s Disease and Ulcerative Colitis. A positive ASCA test is associated with Crohn’s disease in 59-63% of the population with positive test results.

 

WHAT TYPE OF PHYSICIAN SHOULD I SEE?

You should see your primary care physician or a gastroenterologist.

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